ea0073oc13.5 | Oral Communications 13: Pituitary and Neuroendocrinology | ECE2021
Gomez Jesus Perez
, Sáez-Mart Prudencio
, Jiménez-Vacas Juan M.
, Herrero-Aguayo nez-Vacas>
, Pedraza-Arévalo Sergio
, Enrique Gómez-Gómez
, León-González Antonio J.
, Martínez-Fuentes Antonio J.
, Castaño Antonio J.
, Gahete Manuel D.
, Luque Raúl M.
Somatostatin (SST), Cortistatin (CORT), Neuronostatin (NST) and their receptors [SST/CORT-receptors (sst1–5/sst5TMD4-TMD5) and NST-receptor (GPR107)] comprise a hormonal pleiotropic system involved in the regulation of multiple pathophysiological functions. Certain components of this system are dysregulated in endocrine-related cancers, including prostate cancer (PCa), wherein we have found that alterations in specific components of this regulatory system [i.e. NST-GPR10...